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Article

ATP analog-sensitive Pat1 protein kinase for synchronous fission yeast meiosis at physiological temperature.

Cell cycle (Georgetown, Tex.) - 15 Apr 2012

Cipak Lubos, Hyppa Randy W, Smith Gerald R, Gregan Juraj

Abstract excerpt

To study meiosis, synchronous cultures are often indispensable, especially for physical analyses of DNA and proteins. A temperature-sensitive allele of the Pat1 protein kinase (pat1-114) has been widely used to induce synchronous meiosis in the fission yeast Schizosaccharomyces pombe, but pat1-114-induced meiosis differs from wild-type meiosis, and some of these abnormalities might be due to higher temperature...

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Identifiers

PMID: 22487684
DOI: 10.4161/cc.20052
PMCID: PMC3341230

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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