Article
Associations of GSTM1*0 and GSTA1*A genotypes with the risk of cardiovascular death among hemodialyses patients.
BMC nephrology - 14 Jan 2014
Suvakov Sonja, Damjanovic Tatjana, Pekmezovic Tatjana, Jakovljevic Jovana, Savic-Radojevic Ana, Pljesa-Ercegovac Marija, Radovanovic Slavica, Simic Dragan V, Pljesa Steva, Zarkovic Milos, Mimic-Oka Jasmina, Dimkovic Nada, Simic Tatjana
Abstract excerpt
BACKGROUND: The presence of glutathione transferase (GST) M1 null genotype (GSTM1-null) in end-stage renal disease (ESRD) patients is associated with lower overall survival rate in comparison to those with GSTM1-active variants. We examined association between GSTM1 and GSTT1 deletion polymorphisms as well as SNPs in GSTA1/rs3957357 and GSTP1/rs1695 genes with overall and cause-specific cardiovascular mortality...
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