Article
Relationship between GSTs gene polymorphism and susceptibility to end stage renal disease among North Indians.
Renal failure - 1 Jan 2007
Agrawal Suraksha, Tripathi Gaurav, Khan Faisal, Sharma Rajkumar, Baburaj Vinod Pandirikkal
Abstract excerpt
BACKGROUND AND OBJECTIVE: Glutathione-S-transferase (GST) is the superfamily of genes that provides protection to the cells against reactive oxygen species and plays a vital role in phase II of biotransformation of many substances. Overexpression of GST (EC 2.5.1.18) has been documented in the erythrocytes of patients with chronic renal failure, which may be of clinical relevance. Keeping this background in mind,...
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