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Paraoxonase 1 concerning dyslipidaemia, cardiovascular diseases, and mortality in haemodialysis patients.

Scientific reports - 24 Mar 2021

Grzegorzewska Alicja E, Adamska Paulina, Iwańczyk-Skalska Ewa, Ostromecka Kamila, Niepolski Leszek, Marcinkowski Wojciech, Mostowska Adrianna, Warchoł Wojciech, Żaba Czesław, Jagodziński Paweł P

Abstract excerpt

Paraoxonase 1 (PON1) is known for preventing atherosclerosis through lipid-modifying features, antioxidant activity, anti-inflammatory, anti-apoptosis, anti-thrombosis, and anti-adhesion properties. Uremic patients requiring haemodialysis (HD) are especially prone to atherosclerosis and its complications. We analysed the PON1 gene (PON1) polymorphisms and serum PON1 (paraoxonase) activity concerning dyslipidaemia...

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Identifiers

PMID: 33762698
DOI: 10.1038/s41598-021-86231-0
PMCID: PMC7990965

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