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Article

GST M1 polymorphism associates with DNA oxidative damage and mortality among hemodialysis patients.

Journal of the American Society of Nephrology : JASN - 1 Feb 2009

Lin Yi-Sheng, Hung Szu-Chun, Wei Yau-Huei, Tarng Der-Cherng

Abstract excerpt

Leukocyte 8-hydroxy-2'-deoxyguanosine (8-OHdG) is a surrogate marker of oxidant-induced DNA damage in patients undergoing maintenance hemodialysis (MHD). Glutathione S-transferase M1 (GST M1) is a member of the GST family of proteins, which protect cellular DNA against oxidative damage. This study tested the association of a common GST M1 gene polymorphism [GST M1(-)], known to produce a dysfunctional enzyme,...

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Share to DNA Damage
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19056870
DOI: 10.1681/ASN.2008020227
PMCID: PMC2637044

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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