Article
DLG2 rs11607886 polymorphism associated with schizophrenia and precuneus functional changes.
Schizophrenia research - 1 Jun 2025
Zhu HanYu, Wu Zhaoyang, Wang Junxiao, Zhang Enhui, Zhang Sen, Yang Yongfeng, Li Wenqiang, Shi Han, Yang Ge, Lv Luxian, Zhang Yan
Abstract excerpt
BACKGROUND AND HYPOTHESIS: Schizophrenia (SZ) is a severe mental disorder with high heritability. DLG2 encodes the postsynaptic scaffolding protein DLG2 (PSD93, Postsynaptic Density Protein 93), and its variants were associated with an increased risk of SZ. However, the role of DLG2 locus variation in SZ remains elusive. This study aims to investigate the association between DLG2 gene polymorphisms and SZ...
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- Humans
- Male
- Female
- Schizophrenia
- Polymorphism, Single Nucleotide
- Adult
- Magnetic Resonance Imaging