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Article

Population-specific haplotype association of the postsynaptic density gene DLG4 with schizophrenia, in family-based association studies.

PloS one - 1 Jan 2013

Balan Shabeesh, Yamada Kazuo, Hattori Eiji, Iwayama Yoshimi, Toyota Tomoko, Ohnishi Tetsuo, Maekawa Motoko, Toyoshima Manabu, Iwata Yasuhide, Suzuki Katsuaki, Kikuchi Mitsuru, Yoshikawa Takeo

Abstract excerpt

The post-synaptic density (PSD) of glutamatergic synapses harbors a multitude of proteins critical for maintaining synaptic dynamics. Alteration of protein expression levels in this matrix is a marked phenomenon of neuropsychiatric disorders including schizophrenia, where cognitive functions are impaired. To investigate the genetic relationship of genes expressed in the PSD with schizophrenia, a family-based...

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Share to Adaptor Proteins, Signal Transducing
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Disks Large Homolog 4 Protein

Share to Intracellular Signaling Peptides and Proteins

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Share to Proto-Oncogene Proteins c-mdm2

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Source

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Identifiers

PMID: 23936182
DOI: 10.1371/journal.pone.0070302
PMCID: PMC3723755

Genes

DLG4
PSD
DLG1
MDM2
PICK1

Provenance

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