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Article

Biocompatible tissue scaffold compliance promotes salivary gland morphogenesis and differentiation.

Tissue engineering. Part A - 1 Jun 2014

Peters Sarah B, Naim Nyla, Nelson Deirdre A, Mosier Aaron P, Cady Nathaniel C, Larsen Melinda

Abstract excerpt

Substrate compliance is reported to alter cell phenotype, but little is known about the effects of compliance on cell development within the context of a complex tissue. In this study, we used 0.48 and 19.66 kPa polyacrylamide gels to test the effects of the substrate modulus on submandibular salivary gland development in culture and found a significant decrease in branching morphogenesis in explants grown on the...

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Source

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Identifiers

PMID: 24410370
DOI: 10.1089/ten.TEA.2013.0515
PMCID: PMC4029047

Genes

AQP5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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