Article
The BAG homology domain of Snl1 cures yeast prion [URE3] through regulation of Hsp70 chaperones.
G3 (Bethesda, Md.) - 20 Mar 2014
Kumar Navinder, Gaur Deepika, Masison Daniel C, Sharma Deepak
Abstract excerpt
The BAG family of proteins is evolutionarily conserved from yeast to humans and plants. In animals and plants, the BAG family possesses multiple members with overlapping and distinct functions that regulate many cellular processes, such as signaling, protein degradation, and stress response. The only BAG domain protein in Saccharomyces cerevisiae is Snl1, which is anchored to the endoplasmic reticulum through an...
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