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Article

Importance of the Hsp70 ATPase domain in yeast prion propagation.

Genetics - 1 Feb 2007

Loovers Harriët M, Guinan Emma, Jones Gary W

Abstract excerpt

The Saccharomyces cerevisiae non-Mendelian genetic element [PSI+] is the prion form of the translation termination factor Sup35p. The ability of [PSI+] to propagate efficiently has been shown previously to depend upon the action of protein chaperones. In this article we describe a genetic screen that identifies an array of mutants within the two major cytosolic Hsp70 chaperones of yeast, Ssa1p and Ssa2p, which...

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Share to Suppression, Genetic
Share to Adenosine Triphosphatases
Share to Glutathione Peroxidase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Heat-Shock Proteins

Share to HSP70 Heat-Shock Proteins

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Share to Protein Structure, Secondary

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Source

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Identifiers

PMID: 17151238
DOI: 10.1534/genetics.106.066019
PMCID: PMC1800594

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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