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Article

Human proteins curing yeast prions.

Proceedings of the National Academy of Sciences of the United States of America - 7 Nov 2023

Wu Songsong, Edskes Herman K, Wickner Reed B

Abstract excerpt

Recognition that common human amyloidoses are prion diseases makes the use of the Saccharomyces cerevisiae prion model systems to screen for possible anti-prion components of increasing importance. [PSI+] and [URE3] are amyloid-based prions of Sup35p and Ure2p, respectively. Yeast has at least six anti-prion systems that together cure nearly all [PSI+] and [URE3] prions arising in their absence. We made a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37903258
DOI: 10.1073/pnas.2314781120
PMCID: PMC10636303

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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