Genetic study of interactions between the cytoskeletal assembly protein sla1 and prion-forming domain of the release factor Sup35 (eRF3) in Saccharomyces cerevisiae.

doi:10.1093/genetics/153.1.81

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Genetic study of interactions between the cytoskeletal assembly protein sla1 and prion-forming domain of the release factor Sup35 (eRF3) in Saccharomyces cerevisiae.

Genetics - 1 Sept 1999

Bailleul P A, Newnam G P, Steenbergen J N, Chernoff Y O

Abstract excerpt

Striking similarities between cytoskeletal assembly and the "nucleated polymerization" model of prion propagation suggest that similar or overlapping sets of proteins may assist in both processes. We show that the C-terminal domain of the yeast cytoskeletal assembly protein Sla1 (Sla1C) specifically interacts with the N-terminal prion-forming domain (Sup35N) of the yeast release factor Sup35 (eRF3) in the...

Topics

Carrier Proteins
Cinnamates
Cloning, Molecular
Cytoskeletal Proteins
Cytoskeleton
Fungal Proteins
Genes, Fungal
Genes, Suppressor
Heat-Shock Proteins
Humans
Huntingtin Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Hygromycin B

Microbial Sensitivity Tests

Models, Biological

Mutation

Nerve Tissue Proteins

Nuclear Proteins

Paromomycin

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Identifiers

PMID: 10471702
DOI: 10.1093/genetics/153.1.81
PMCID: PMC1460745

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