Article
The relationship between serum bilirubin and Crohn's disease.
Inflammatory bowel diseases - 1 Mar 2014
Leníček Martin, Duricová Dana, Hradsky Ondrej, Dušátková Petra, Jirásková Alena, Lukáš Milan, Nachtigal Petr, Vítek Libor
Abstract excerpt
BACKGROUND: The oxidative stress is thought to play an important role in Crohn's disease (CD). As serum bilirubin represents the major endogenous antioxidant, this article aimed to evaluate in a clinical study, whether serum bilirubin levels and genes affecting its systemic concentrations are associated with CD. METHODS: This exploratory case-control study was based on pediatric (n = 119) and adult (n = 504)...
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