Article
Characteristics of the heme catabolic pathway in mild unconjugated hyperbilirubinemia and their associations with inflammation and disease prevention.
Scientific reports - 7 Apr 2017
Mölzer Christine, Wallner Marlies, Kern Carina, Tosevska Anela, Zadnikar René, Doberer Daniel, Marculescu Rodrig, Wagner Karl-Heinz
Abstract excerpt
Heme catabolism exerts physiological functions that impact health through depressing inflammation. Upon reactive pathway progression, as in Gilbert's Syndrome (GS; UGT1A1*28 polymorphism), aggravated health effects have been determined. Based on lower inflammation and improved metabolic health reported for GS, inter-group differences in heme catabolism were explored. Therefore, a case-control study including 120...
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