Article
A transcript perspective on evolution.
IEEE/ACM transactions on computational biology and bioinformatics - 1 Jan 2000
Christinat Yann, Moret Bernard M E
Abstract excerpt
Alternative splicing is now recognized as a major mechanism for transcriptome and proteome diversity in higher eukaryotes, yet its evolution is poorly understood. Most studies focus on the evolution of exons and introns at the gene level, while only few consider the evolution of transcripts. In this paper, we present a framework for transcript phylogenies where ancestral transcripts evolve along the gene tree by...
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