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Article

Significant association of interleukin-4 gene intron 3 VNTR polymorphism with susceptibility to knee osteoarthritis.

Gene - 1 Mar 2014

Yigit Serbulent, Inanir Ahmet, Tekcan Akın, Tural Ercan, Ozturk Gokhan Tuna, Kismali Gorkem, Karakus Nevin

Abstract excerpt

OBJECTIVE: Interleukin-4 (IL-4) is a strong chondroprotective cytokine and polymorphisms within this gene may be a risk factor for osteoarthritis (OA). We aimed to investigate genotype and allele frequencies of IL-4 gene intron 3 variable number of tandem repeats (VNTR) polymorphism in patients with knee OA in a Turkish population. METHODS: The study included 202 patients with knee OA and 180 healthy controls....

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Identifiers

PMID: 24406619
DOI: 10.1016/j.gene.2013.12.060

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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