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Article

β-1,4-Galactosyltransferase III suppresses β1 integrin-mediated invasive phenotypes and negatively correlates with metastasis in colorectal cancer.

Carcinogenesis - 1 Jun 2014

Chen Chia-Hua, Wang Shui-Hua, Liu Chiung-Hui, Wu Yi-Ling, Wang Wei-Jen, Huang John, Hung Ji-Shiang, Lai I-Rue, Liang Jin-Tung, Huang Min-Chuan

Abstract excerpt

Metastasis often occurs in colorectal cancer (CRC) patients and is the main difficulty in cancer treatment. The upregulation of poly-N-acetyllactosamine-related glycosylation is found in CRC patients and is associated with progression and metastasis in cancer. β-1,4-Galactosyltransferase III (B4GALT3) is an enzyme responsible for poly-N-acetyllactosamine synthesis, and therefore, we investigated its expression in...

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PMID: 24403309
DOI: 10.1093/carcin/bgu007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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