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O-GlcNAcylation mediates metastasis of cholangiocarcinoma through FOXO3 and MAN1A1

18 Jun 2018

Abstract excerpt

The leading cause of death in cancer patients is metastasis, for which an effective treatment is still necessary. During metastasis, cancer cells aberrantly express several glycans that are correlated with poor patient outcome. This study was aimed toward exploring the effects of O-GlcNAcylation on membranous N-glycans that are associated with the progression of cholangiocarcinoma (CCA). Global O-GlcNAcylation in...

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Share to Cholangiocarcinoma and Gallbladder Cancer Studies
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PMID: 29915392
DOI: 10.1038/s41388-018-0366-1

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