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Article

Beta1,4-N-acetylgalactosaminyltransferase III enhances malignant phenotypes of colon cancer cells.

Molecular cancer research : MCR - 1 Jun 2007

Huang John, Liang Jin-Tung, Huang Hsiu-Chin, Shen Tang-Long, Chen Hsiao-Yu, Lin Neng-Yu, Che Mei-Ieng, Lin Wei-Chou, Huang Min-Chuan

Abstract excerpt

The enzyme beta1,4-N-acetylgalactosaminyltransferase III (beta4GalNAc-T3) exhibits in vitro activity of synthesizing N,N'-diacetyllactosediamine, GalNAcbeta1,4GlcNAc. Here, we investigate the expression of beta4GalNAc-T3 in primary colon tumors and the effects of its overexpression on HCT116 colon cancer cells. Real-time reverse transcription-PCR showed that the expression of beta4GalNAc-T3 was up-regulated in...

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PMID: 17579116
DOI: 10.1158/1541-7786.MCR-06-0431

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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