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Article

Role of the polypeptide N-acetylgalactosaminyltransferase 3 in ovarian cancer progression: possible implications in abnormal mucin O-glycosylation.

Oncotarget - 30 Jan 2014

Wang Zhi-Qiang, Bachvarova Magdalena, Morin Chantale, Plante Marie, Gregoire Jean, Renaud Marie-Claude, Sebastianelli Alexandra, Bachvarov Dimcho

Abstract excerpt

Previously, we have identified the polypeptide N-acetylgalactosaminyltransferase 3 (GALNT3) gene as notably hypomethylated in low-malignant potential (LMP) and high-grade (HG) serous epithelial ovarian tumors, compared to normal ovarian tissues. Here we show that GALNT3 is strongly overexpressed in HG serous EOC tumors as compared to normal ovarian tissue. Moreover, the GALNT3 expression significantly correlated...

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Share to Carcinoma, Ovarian Epithelial
Share to Cell Growth Processes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glycosylation

Share to Mucins

Share to N-Acetylgalactosaminyltransferases

Share to Neoplasms, Glandular and Epithelial

Share to Polypeptide N-acetylgalactosaminyltransferase

Share to Tissue Array Analysis

Source

Open in PubMed Open full text

Identifiers

PMID: 24504219
DOI: 10.18632/oncotarget.1652
PMCID: PMC3964228

Genes

GALNT3
MUC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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