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Article

Isocitrate dehydrogenase 2 mutation is a frequent event in osteosarcoma detected by a multi-specific monoclonal antibody MsMab-1.

Cancer medicine - 1 Dec 2013

Liu Xing, Kato Yukinari, Kaneko Mika Kato, Sugawara Masato, Ogasawara Satoshi, Tsujimoto Yuta, Naganuma Yasushi, Yamakawa Mitsunori, Tsuchiya Takashi, Takagi Michiaki

Abstract excerpt

Somatic mutations of isocitrate dehydrogenase (IDH) 1 and IDH2 occur in gliomas, acute myeloid leukemia, and cartilaginous tumors. Somatic mosaic IDH1/2 mutations are also reported in Ollier disease and Maffucci syndrome, which are characterized by multiple central cartilaginous tumors. Although...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24403254
DOI: 10.1002/cam4.149
PMCID: PMC3892385

Genes

IDH2
IDH1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24403254-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

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Isocitrate dehydrogenase 2 mutation is a frequent event in osteosarcoma detected by a multi-specific monoclonal antibody MsMab-1.PMID 24403254Read ↗

Isocitrate dehydrogenase mutation is frequently observed in giant cell tumor of bone.Semantic proximity Read ↗

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Diagnostic advantage of double immunohistochemistry using two mutation-specific anti-IDH antibodies (HMab-1 and MsMab-1) in gliomas.Semantic proximity Read ↗

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