Article
Molecular distinction of chondrosarcoma from chondroblastic osteosarcoma through IDH1/2 mutations.
The American journal of surgical pathology - 1 Jun 2013
Kerr Darcy A, Lopez Hector U, Deshpande Vikram, Hornicek Francis J, Duan Zhenfeng, Zhang Yaxia, Rosenberg Andrew E, Borger Darrel R, Nielsen G Petur
Abstract excerpt
Distinguishing chondrosarcoma from chondroblastic osteosarcoma can be difficult and highly subjective, especially on a small biopsy specimen. This distinction is critical in determining the most accurate prognosis and appropriate treatment modality, as adjuvant chemotherapy with surgery is standard treatment for osteosarcoma, whereas chondrosarcoma is generally treated by surgical excision alone. Cartilaginous...
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