Analysis of the rs10046 polymorphism of aromatase (CYP19) in premenopausal onset of human breast cancer.

doi:10.3390/ijms15010712

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Article

Analysis of the rs10046 polymorphism of aromatase (CYP19) in premenopausal onset of human breast cancer.

International journal of molecular sciences - 7 Jan 2014

Zins Karin, Mogg Maurice, Schneeberger Christian, Abraham Dietmar, Schreiber Martin

Abstract excerpt

The CYP19 gene encodes aromatase, an enzyme catalyzing the conversion of androgens to estrogens. Studies analyzing associations between single nucleotide polymorphisms in CYP19 and breast cancer risk have shown inconsistent results. The rs10046 polymorphism is located in the 3' untranslated region of the CYP19 gene, but the influence of this polymorphism on breast cancer risk is unclear. In this study, we...

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PMID: 24402127
DOI: 10.3390/ijms15010712
PMCID: PMC3907833

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.