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Article

β-catenin deacetylation is essential for WNT-induced proliferation of breast cancer cells.

Molecular medicine reports - 1 Mar 2014

Wang Shao-Hua, Li Ning, Wei Yao, Li Qiu-Rong, Yu Ze-Ping

Abstract excerpt

Deregulation of the WNT signaling pathway is associated with the development and progression of breast cancer. β-catenin mutations have been found to constitutively activate β-catenin-T-cell factor (TCF) signaling in other types of cancer. β-catenin acetylation regulates β-catenin-TCF4 interaction in WNT signaling, but it remains unknown whether the acetylation of β-catenin is involved in WNT-induced...

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Share to Acetylation
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24401947
DOI: 10.3892/mmr.2014.1889

Genes

HDAC6
TCF4
TCF7

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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