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Article

GalNAc-T14 promotes metastasis through Wnt dependent HOXB9 expression in lung adenocarcinoma.

Oncotarget - 8 Dec 2015

Kwon Ok-Seon, Oh Ensel, Park Jeong-Rak, Lee Ji-Seon, Bae Gab-Yong, Koo Jae-Hyung, Kim Hyongbum, Choi Yoon L, Choi Young Soo, Kim Jhingook, Cha Hyuk-Jin

Abstract excerpt

While metastasis, the main cause of lung cancer-related death, has been extensively studied, the underlying molecular mechanism remains unclear. A previous clinicogenomic study revealed that expression of N-acetylgalactosaminyltransferase (GalNAc-T14), is highly inversely correlated with recurrence-free survival in those with non-small cell lung cancer (NSCLC). However, the underlying molecular mechanism(s) has...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26544896
DOI: 10.18632/oncotarget.6019
PMCID: PMC4747198

Genes

HOXB9

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