Article
SET7/9 regulates cancer cell proliferation by influencing β-catenin stability.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Oct 2015
Shen Changchun, Wang Donglai, Liu Xiangyu, Gu Bo, Du Yipeng, Wei Fu-Zheng, Cao Lin-Lin, Song Boyan, Lu Xiaopeng, Yang Qiaoyan, Zhu Qian, Hou Tianyun, Li Meiting, Wang Lina, Wang Haiying, Zhao Ying, Yang Yang, Zhu Wei-Guo
Abstract excerpt
β-Catenin, which is a key mediator of the wingless-integration site (Wnt)/β-catenin signaling pathway, plays an important role in cell proliferation, cell fate determination, and tumorigenesis, by regulating the expression of a wide range of target genes. Although a variety of posttranslational modifications are involved in β-catenin activity, the role of lysine methylation in β-catenin activity is largely...
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