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Article

Effect of substrate rigidity in tissue culture on the function of insulin-secreting INS-1E cells.

Journal of tissue engineering and regenerative medicine - 1 Jan 2017

Naujok O, Bandou Y, Shikama Y, Funaki M, Lenzen S

Abstract excerpt

Insulin-secreting INS-1E cells are a useful tool in diabetes research. However, during permanent culture the cells tend to lose their β cell phenotype, with resultant loss of insulin-secretory responsiveness. This can be at least partially attributed to inappropriate cell culture conditions. One...

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PMID: 24399617
DOI: 10.1002/term.1857

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INS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24399617-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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