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Article

Substrate stiffness regulates type II diabetic fibroblast phenotype and metabolic activity.

Biochemical and biophysical research communications - 21 May 2024

Huffer Amelia, Ozdemir Tugba

Abstract excerpt

In people living with diabetes, impaired wound healing is a major concern as the formation of ulcerated wounds can drastically reduce both the effectiveness of the healing process and the quality of life of the patient. The healing of dermal wounds in particular involves a patient's fibroblasts building up a strong extracellular matrix of mostly collagen I and collagen III fibers, which the cells of diabetic...

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PMID: 38574608
DOI: 10.1016/j.bbrc.2024.149833

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