Article
Effects of poly-L-lysine and collagen on FH-B-TPN cell differentiation into endocrine cell phenotype.
Transplantation proceedings - 1 Mar 2008
Racanicchi L, Conti V, Basta G, Montanucci P, Calafiore R
Abstract excerpt
Pdx-1 genetically engineered FH-B-TPN cells might represent a source for insulin-secreting cells. We then have tested whether poly-L-lysine (PLL) and collagen (C) exposure in vitro promote three-dimensional particle formation and differentiation toward an endocrine cell phenotype. On these matrices, we observed that FH-B-TPN cells showed a tendency to either aggregate when seeded on PLL or to form uniform cell...
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