Article
Improved phenotype of rat islets in a macrocapsule by co-encapsulation with cross-linked Hb.
Journal of biomaterials science. Polymer edition - 1 Jan 2005
Kim Yong Yeon, Chae Su Young, Kim Sungwon, Byun Youngro, Bae You Han
Abstract excerpt
A number of rat islets were co-encapsulated in a diffusion chamber-type device, i.e., macrocapsule, with a thermoreversible polymeric extracellular matrix (ECM) and bioactive ingredient of cross-linked hemoglobin (Hb-C). The ECM was formed from an aqueous solution of N-isopropyl-acrylamide co-polymers with a small amount of acrylic acid, which exhibited unique sol-gel transition in a temperature range of 30-34...
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