Article
Synergistic effect between polymorphisms of PPARA and ABCA1 genes on the premature coronary artery disease.
Acta cardiologica - 1 Jun 2007
Balcerzyk Anna, Zak Iwona, Krauze Jolanta
Abstract excerpt
OBJECTIVE: Progression of atherosclerosis, the main reason of cardiovascular diseases, depends on multiple genetic and environmental factors. Polymorphic variants of genes involved in the lipids metabolism may genetically differentiate human populations and determine a susceptibility to the disease. The aim of the present study was to evaluate a possible interaction between R219K polymorphism of ABCA1 gene and G...
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