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Article

Translation enhancing ACA motifs and their silencing by a bacterial small regulatory RNA.

PLoS genetics - 1 Jan 2014

Yang Qi, Figueroa-Bossi Nara, Bossi Lionello

Abstract excerpt

GcvB is an archetypal multi-target small RNA regulator of genes involved in amino acid uptake or metabolism in enteric bacteria. Included in the GcvB regulon is the yifK locus, encoding a conserved putative amino acid transporter. GcvB inhibits yifK mRNA translation by pairing with a sequence immediately upstream from the Shine-Dalgarno motif. Surprisingly, we found that some target sequence mutations that...

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Share to Amino Acid Transport Systems
Share to Escherichia coli Proteins
Share to Gene Expression Regulation, Bacterial

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Nucleotide Motifs

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Source

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Identifiers

PMID: 24391513
DOI: 10.1371/journal.pgen.1004026
PMCID: PMC3879156

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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