Article
The 3' proximal translational enhancer of Turnip crinkle virus binds to 60S ribosomal subunits.
RNA (New York, N.Y.) - 1 Nov 2008
Stupina Vera A, Meskauskas Arturas, McCormack John C, Yingling Yaroslava G, Shapiro Bruce A, Dinman Jonathan D, Simon Anne E
Abstract excerpt
During cap-dependent translation of eukaryotic mRNAs, initiation factors interact with the 5' cap to attract ribosomes. When animal viruses translate in a cap-independent fashion, ribosomes assemble upstream of initiation codons at internal ribosome entry sites (IRES). In contrast, many plant viral genomes do not contain 5' ends with substantial IRES activity but instead have 3' translational enhancers that...
Topics
- 3' Untranslated Regions
- Base Sequence
- Carmovirus
- Enhancer Elements, Genetic
- Genome, Viral
- Molecular Sequence Data
- Mutation
- Protein Biosynthesis
- RNA, Transfer, Amino Acyl
- RNA, Viral
- Ribosome Subunits, Large, Eukaryotic