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Article

Pervasive post-transcriptional control of genes involved in amino acid metabolism by the Hfq-dependent GcvB small RNA.

Molecular microbiology - 1 Sept 2011

Sharma Cynthia M, Papenfort Kai, Pernitzsch Sandy R, Mollenkopf Hans-Joachim, Hinton Jay C D, Vogel Jörg

Abstract excerpt

GcvB is one of the most highly conserved Hfq-associated small RNAs in Gram-negative bacteria and was previously reported to repress several ABC transporters for amino acids. To determine the full extent of GcvB-mediated regulation in Salmonella, we combined a genome-wide experimental approach with biocomputational target prediction. Comparative pulse expression of wild-type versus mutant sRNA variants revealed...

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PMID: 21696468
DOI: 10.1111/j.1365-2958.2011.07751.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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