Upstream translation initiation expands the coding capacity of segmented negative-strand RNA viruses

Abstract excerpt

Segmented negative-strand RNA viruses (sNSVs) include the influenza viruses, the bunyaviruses, and other major pathogens of humans, other animals and plants. The genomes of these viruses are extremely short. In response to this severe genetic constraint, sNSVs use a variety of strategies to maximise their coding potential. Because the eukaryotic hosts parasitized by sNSVs can regulate gene expression through low l...

Topics

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• Mosquito-borne diseases and control
• RNA and protein synthesis mechanisms
• RNA regulation and disease
• RNA Research and Splicing
• Viral Infections and Immunology Research
• Viral Infections and Outbreaks Research
• Viral Infections and Vectors
• Virology and Viral Diseases

Identifiers and source

Literature Corpus work

e1f19bd7-cacf-5c1a-a512-3285d76f9519

DOI

10.1101/795815