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Article

Translation inhibition of the Salmonella fliC gene by the fliC 5' untranslated region, fliC coding sequences, and FlgM.

Journal of bacteriology - 1 Jun 2006

Rosu Valentina, Chevance Fabienne F V, Karlinsey Joyce E, Hirano Takanori, Hughes Kelly T

Abstract excerpt

The 5'-untranslated region (5'UTR) of the fliC flagellin gene of Salmonella contains sequences critical for efficient fliC mRNA translation coupled to assembly. In a previous study we used targeted mutagenesis of the 5' end of the fliC gene to isolate single base changes defective in fliC gene translation. This identified a predicted stem-loop structure, SL2, as an effector of normal fliC mRNA translation. A...

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Identifiers

PMID: 16740956
DOI: 10.1128/JB.01552-05
PMCID: PMC1482935

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