Article
Interleukin (IL)-21 promoter polymorphism increases the risk of thyroid cancer in Chinese population.
Gene - 1 Mar 2014
Xiao Mang, Hu Sunhong, Tang Jianguo, Zhang Lei, Jiang Huifen
Abstract excerpt
Polymorphisms in Interleukin (IL)-21 have been researched in several cancers, but the association between IL-21 polymorphisms and thyroid cancer remains unclarified. This case-control study explored the role of five tagSNPs (rs12508721C>T, rs907715G>A, rs13143866G>A, rs2221903A>G and rs4833837A>G) in IL-21 gene in thyroid cancer development. IL-21 genotypes were examined in 615 thyroid cancer patients and 600...
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