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Article

Plasma interleukin-21 levels and genetic variants are associated with susceptibility to rheumatoid arthritis.

BMC musculoskeletal disorders - 5 Mar 2021

Hao Youguo, Xie Lijun, Xia Jing, Liu Zhen, Yang Baoxiu, Zhang Minqin

Abstract excerpt

BACKGROUND: Rheumatoid Arthritis (RA) is a chronic inflammatory condition characterized by autoantibodies development and an elevated spectrum of pro-inflammatory cytokines. Previous reports highlighted a relationship between IL-21and the pathogenesis of RA. Although elevated IL-21 levels have been reported in RA patients, the association of common IL-21 genetic variants with a predisposition to RA development in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33673829
DOI: 10.1186/s12891-021-04111-0
PMCID: PMC7936495

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