Genetic variant rs401681 at 5p15.33 modifies susceptibility to lung cancer but not esophageal squamous cell carcinoma.

doi:10.1371/journal.pone.0084277

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Article

Genetic variant rs401681 at 5p15.33 modifies susceptibility to lung cancer but not esophageal squamous cell carcinoma.

PloS one - 1 Jan 2013

Jiang Man, Wu Haijian, Qin Chengyong

Abstract excerpt

BACKGROUND: The human 5p15.33 locus contains two well-known genes, the telomerase reverse transcriptase (TERT) and cleft lip and palate transmembrane 1-like (CLPTM1L) genes, which have been implicated in carcinogenesis. A common sequence variant, rs401681, located in an intronic region of CLPTM1L, has been reported to be associated with lung cancer risk based on genome-wide association study. However, subsequent...

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PMID: 24386361
DOI: 10.1371/journal.pone.0084277
PMCID: PMC3875515

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TERT

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Genetic variant rs401681 at 5p15.33 modifies susceptibility to lung cancer but not esophageal squamous cell carcinoma.PMID 24386361Read ↗

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