Article
Genetic risk factors for nonsyndromic cleft lip with or without cleft palate in a Brazilian population with high African ancestry.
American journal of medical genetics. Part A - 1 Oct 2015
do Rego Borges Andrea, Sá Jamile, Hoshi Ryuichi, Viena Camila Sane, Mariano Lorena C, de Castro Veiga Patricia, Medrado Alena Peixoto, Machado Renato Assis, de Aquino Sibele Nascimento, Messetti Ana Camila, Spritz Richard A, Coletta Ricardo D, Reis Silvia R A
Abstract excerpt
Nonsyndromic cleft lip with or without cleft palate (NSCL ± P) is the most common orofacial birth defect, exhibiting variable prevalence around the world, often attributed to ethnic and environmental differences. Linkage analyses and genome-wide association studies have identified several genomic susceptibility regions for NSCL ± P, mostly in European-derived or Asian populations. Genetic predisposition to NSCL ±...
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