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Article

Polymorphisms of tumor necrosis factor alpha gene and coronary heart disease in a Chinese Han population: interaction with cigarette smoking.

Thrombosis research - 1 Apr 2009

Hou Liping, Huang Jianfeng, Lu Xiangfeng, Wang Laiyuan, Fan Zhongjie, Gu Dongfeng

Abstract excerpt

INTRODUCTION: Tumor necrosis factor alpha (TNF-alpha) is a primary pro-inflammatory cytokines and has been implicated in cardiovascular disease pathogenesis. Relationship between polymorphisms in TNF-alpha gene and coronary heart disease (CHD) has been reported, but remains a controversial one. MATERIALS AND METHODS: A single nucleotide polymorphism (SNP) discovery in a total of 4739 base pairs in the promoter...

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PMID: 18814905
DOI: 10.1016/j.thromres.2008.07.016

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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