Article
Association of G308A and G238A Polymorphisms of the TNF-α Gene with Risk of Coronary Heart Disease: Systematic Review and Meta-analysis.
Archives of medical research - 1 Oct 2016
Pulido-Gómez Karely, Hernández-Díaz Yazmín, Tovilla-Zárate Carlos Alfonso, Juárez-Rojop Isela Esther, González-Castro Thelma Beatriz, López-Narváez María Lilia, Alpuin-Reyes Mariela
Abstract excerpt
BACKGROUND AND AIMS: It is widely acknowledged that coronary heart disease (CHD) has a genetic influence. One of the most promising candidate genes is tumor necrosis factor-alpha (TNF-α). Although there have been several positive studies associating the TNF-α gene and CHD, the evidence is not entirely consistent. The aim of the study was to evaluate the role of the TNF-α gene in CHD using combined evidence by...
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