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Article

Pulmonary microRNA profiling: implications in upper lobe predominant lung disease

30 May 2017

Abstract excerpt

Numerous pulmonary diseases manifest with upper lobe predominance including cystic fibrosis, smoking-related chronic obstructive pulmonary disease, and tuberculosis. Zonal hypoxia, characteristic of these pulmonary maladies, and oxygen stress in general is known to exert profound effects on various important aspects of cell biology. Lung macrophages are major participants in the pulmonary innate immune response...

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Share to Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
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PMID: 28572860
DOI: 10.1186/s13148-017-0355-1

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