Article
Bioinformatics-based identification of potential microRNA biomarkers in frequent and non-frequent exacerbators of COPD.
International journal of chronic obstructive pulmonary disease - 1 Jan 2000
Liu Xiao, Qu Jingge, Xue Weixiao, He Liangai, Wang Jun, Xi Xuejiao, Liu Xiaoxia, Yin Yunhong, Qu Yiqing
Abstract excerpt
OBJECTIVES: MicroRNAs (miRNAs) play essential roles in the development of COPD. In this study, we aimed to identify and validate potential miRNA biomarkers in frequent and non-frequent exacerbators of COPD patients using bioinformatic analysis. MATERIALS AND METHODS: The candidate miRNA biomarkers in COPD were screened from Gene Expression Omnibus (GEO) dataset and identified using GEO2R online tool. Then, we...
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