Article
Extracting predictive SNPs in Crohn's disease using a vacillating genetic algorithm and a neural classifier in case-control association studies.
Computers in biology and medicine - 1 Jan 2014
Anekboon Khantharat, Lursinsap Chidchanok, Phimoltares Suphakant, Fucharoen Suthat, Tongsima Sissades
Abstract excerpt
Crohn's disease is an inflammatory bowel disease. Because of strong heritability, it is possible to deploy the pattern of DNA variations, such as single nucleotide polymorphisms (SNPs), to accurately predict the state of this disease. However, there are many possible SNP subsets, which make finding a best set of SNPs to achieve the highest prediction accuracy impossible in one patient's lifetime. In this paper, a...
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