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Article

Association of genetic profiles to Crohn's disease by linear combinations of single nucleotide polymorphisms.

Artificial intelligence in medicine - 1 Jun 2009

D'Addabbo Annarita, Latiano Anna, Palmieri Orazio, Creanza Maria Teresa, Maglietta Rosalia, Annese Vito, Ancona Nicola

Abstract excerpt

MOTIVATIONS: A large number of single nucleotide polymorphisms (SNPs) are supposed to be involved in onset, differentiation and development of complex diseases. Univariate analysis is limited in studying complex traits since does not take into account gene-gene interaction, and the correlation of multiple SNPs with a specific phenotype. Moreover it might underestimate gene variants with weaker genetic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18804983
DOI: 10.1016/j.artmed.2008.07.012

Genes

TNF
DLG5
PTPN22

Variants

rs124869
rs124869

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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