Article
A genetic algorithm-support vector machine method with parameter optimization for selecting the tag SNPs.
Journal of biomedical informatics - 1 Apr 2013
Ilhan Ilhan, Tezel Gülay
Abstract excerpt
SNPs (Single Nucleotide Polymorphisms) include millions of changes in human genome, and therefore, are promising tools for disease-gene association studies. However, this kind of studies is constrained by the high expense of genotyping millions of SNPs. For this reason, it is required to obtain a suitable subset of SNPs to accurately represent the rest of SNPs. For this purpose, many methods have been developed...
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