Article
Detection of haplotypes associated with prenatal death in dairy cattle and identification of deleterious mutations in GART, SHBG and SLC37A2.
PloS one - 1 Jan 2013
Fritz Sébastien, Capitan Aurelien, Djari Anis, Rodriguez Sabrina C, Barbat Anne, Baur Aurélia, Grohs Cécile, Weiss Bernard, Boussaha Mekki, Esquerré Diane, Klopp Christophe, Rocha Dominique, Boichard Didier
Abstract excerpt
The regular decrease of female fertility over time is a major concern in modern dairy cattle industry. Only half of this decrease is explained by indirect response to selection on milk production, suggesting the existence of other factors such as embryonic lethal genetic defects. Genomic regions harboring recessive deleterious mutations were detected in three dairy cattle breeds by identifying frequent haplotypes...
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