Four novel candidate causal variants for deficient homozygous haplotypes in Holstein cattle.

doi:10.1038/s41598-022-09403-6

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Article

Four novel candidate causal variants for deficient homozygous haplotypes in Holstein cattle.

Scientific reports - 31 Mar 2022

Häfliger Irene M, Spengeler Mirjam, Seefried Franz R, Drögemüller Cord

Abstract excerpt

Mendelian variants can determine both insemination success and neonatal survival and thus influence fertility and rearing success of cattle. We present 24 deficient homozygous haplotype regions in the Holstein population of Switzerland and provide an overview of the previously identified haplotypes in the global Holstein breed. This study encompasses massive genotyping, whole-genome sequencing (WGS) and phenotype...

Topics

Alleles
Animals
Cattle
Female
Fertility
Genotype
Haplotypes
Homozygote

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Identifiers

PMID: 35361830
DOI: 10.1038/s41598-022-09403-6
PMCID: PMC8971413

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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