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Article

HLA-G UTR haplotype conservation in the Malian population: association with soluble HLA-G.

PloS one - 1 Jan 2013

Carlini Federico, Traore Karim, Cherouat Nissem, Roubertoux Pierre, Buhler Stéphane, Cortey Martì, Simon Sophie, Doumbo Ogobara, Chiaroni Jacques, Picard Christophe, Di Cristofaro Julie

Abstract excerpt

The HLA-G molecule plays an important role in immunomodulation. In a previous study carried out on a southern French population our team showed that HLA-G haplotypes, defined by SNPs in the coding region and specific SNPs located in 5'URR and 3'UTR regulatory regions, are associated with differential soluble HLA-G expression (sHLA-G). Furthermore, the structure of these HLA-G haplotypes appears to be conserved in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24376542
DOI: 10.1371/journal.pone.0082517
PMCID: PMC3871591

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